NanoBioPhysik und Medizinische Physik   (Prof. Schäffer)
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Publications

J. Rheinlaender, A. Gräbner, L. Ott, A. Burkovski and T.E. Schäffer, “Contour and persistence length of Corynebacterium diphtheriae pili by atomic force microscopy.” European Biophysics Journal (in press, 2012)

C. Braunsmann, C.M. Hammer, J. Rheinlaender, F.E. Kruse, T.E. Schäffer and U. Schlötzer-Schrehardt, “Evaluation of lamina cribrosa and peripapillary sclera stiffness in pseudo-exfoliation and normal eyes by atomic force microscopy.” Investigative Ophthalmology & Visual Science (in press, 2012)
Abstract | preprint

B. Fabry, A.H. Klemm, S. Kienle, T.E. Schäffer and W.H. Goldmann, “Focal adhesion kinase stabilizes the cytoskeleton.” Biophysical Journal 101, 2131–2138 (2011).
Abstract | PDF (1267 kB)

J. Rheinlaender, N.A. Geisse, R. Proksch and T.E. Schäffer, “Comparison of scanning ion conductance microscopy with atomic force microscopy for cell imaging.” Langmuir 27, 697-704 (2011).
Abstract | PDF (4924 kB)

C. Braunsmann and T.E. Schäffer, “High-speed atomic force microscopy for large scan sizes using small cantilevers.” Nanotechnology 21, 225705 (2010).
Abstract | PDF (1020 kB)

L. Ott, M. Höller, J. Rheinlaender, T.E. Schäffer, M. Hensel and A. Burkovski, “Strain-specific differences in pili formation and the interaction of Corynebacterium diphtheriae with host cells.” BMC Microbiology 10:257 (2010).
Abstract | PDF (open access) (1547 kB)

A.H. Klemm, S. Kienle, J. Rheinlaender, T.E. Schäffer and W.H. Goldmann, “The Influence of Pyk2 on the Mechanical Properties in Fibroblasts.” Biochemical and Biophysical Research Communications 393, 694-697 (2010).
Abstract | PDF (325 kB)

J. Rheinlaender and T.E. Schäffer, “Scanning Ion Conductance Microscopy”, in “Scanning Probe Microscopy of Functional Materials”, S.V. Kalinin and A. Gruverman, eds., Springer Verlag, Berlin, Heidelberg, New York, ISBN 978-1441965677, p.433-460 (2010).
Link to Springer

L. Ott, M. Höller, R.G. Gerlach, M. Hensel, J. Rheinlaender, T.E. Schäffer and A. Burkovski, “Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells.” BMC Microbiology 10:2 (2010).
Abstract | PDF (open access) (2955 kB)

J. Rheinlaender and T.E. Schäffer, “Image formation and resolution in scanning ion conductance microscopy.” Journal of Applied Physics 105, 094905 (2009).
Abstract | PDF (834 kB) | Free PDF (s. AIP copyright note below)

M. Böcker, S. Muschter, E. Schmitt, C. Steinem, and T.E. Schäffer, “Imaging and patterning of pore-suspending membranes with scanning ion conductance microscopy.” Langmuir 25, 3022-3028 (2009).
Abstract | PDF (1174 kB)

M. Böcker, H. Fuchs and T.E. Schäffer, “Scanning Ion Conductance Microscopy of Cellular and Artificial Membranes”, in “Nanotechnology: Volume 6: Nanoprobes”, H. Fuchs, ed., WILEY-VCH Verlag, Weinheim, ISBN 978-3-527-31733-2, p.197-212 (2009).
Link to Wiley-VCH

D. Sánchez, N. Johnson, C. Li, P. Novak, J. Rheinlaender, Y. Zhang, U. Anand, P. Anand, J. Gorelik, G.I. Frolenkov, C. Benham, M. Lab, V.P. Ostanin, T.E. Schäffer, D. Klenerman and Y.E. Korchev, “Non-contact measurement of the local mechanical properties of living cells using pressure applied via a pipette.” Biophysical Journal 95, 3017–3027 (2008).
Abstract | PDF (946 kB)

A. Heredia, C.C. Bui, U. Suter, P. Young and T.E. Schäffer, “AFM combines functional and morphological analysis of peripheral myelinated and demyelinated nerve fibers.” NeuroImage 37, 1218-1226 (2007).
Abstract | PDF (1126 kB)

C. Riethmüller, T.E. Schäffer, F. Kienberger, W. Stracke and H. Oberleithner, “Vacuolar structures can be identified by AFM elasticity mapping.” Ultramicroscopy 107, 895–901 (2007).
Abstract | PDF (1358 kB)

M. Böcker, B. Anczykowski, J. Wegener and T.E. Schäffer, “Scanning ion conductance microscopy with distance-modulated shear force control.” Nanotechnology 18, 145505 (2007).
Abstract | PDF (777 kB)
(This article was featured under "nanotechnology journal highlights" on nanotechweb.org)

A. Heredia, M. Aguilar-Franco, C. Magaña, C. Flores, C. Piña, R. Velázquez, T.E. Schäffer, L. Bucio and V.A. Basiuk, “Structure and interactions of calcite spherulites with alpha-chitin in the brown shrimp (Penaeus aztecus) shell.” Materials Science and Engineering C 27, 8-13 (2007).
Abstract | PDF (542 kB)

M. Böcker and T.E. Schäffer, “Scanning Ion Conductance Microscopy” G.I.T. Imaging & Microscopy 02/2007, 30-32 (2007).

T.E. Schäffer, “Low-noise methods for optical measurements of cantilever deflections”, in “Applied Scanning Probe Methods V”, B. Bhushan, H. Fuchs and S. Kawata, eds., Springer Verlag, Berlin, Heidelberg, New York, ISBN 3-540-37315-2, p.51-74 (2007).
Link to Springer

T.E. Schäffer, B. Anczykowski, M. Böcker and H. Fuchs, “Shear-Force-Controlled Scanning Ion Conductance Microscopy”, in “Nanobiotechnology II: More Concepts and Applications”, C.M. Niemeyer and C.A. Mirkin, eds., WILEY-VCH Verlag, Weinheim, ISBN 978-3-527-31673-1, p.197-212 (2007).
Link to Wiley-VCH

S.M. Cook, T.E. Schäffer, K.M. Chynoweth, M. Wigton, R.W Simmonds and K.M. Lang, “Practical implementation of dynamic methods for measuring atomic force microscope cantilever spring constants.” Nanotechnology 17, 2135-2145 (2006).
Abstract | PDF (517 kB)

T.E. Schäffer, “High-speed atomic force microscopy of biomolecules in motion”, in “Force Microscopy: Applications in Biology and Medicine”, B. Jena, H. Hörber, eds., WILEY-VCH Verlag, Weinheim, ISBN 0-471-39628-1, p. 221-247 (2006).
Link to Wiley-VCH

T.E. Schäffer, B. Anczykowski and H. Fuchs, “Scanning Ion Conductance Microscopy”, in “Applied Scanning Probe Methods II”, B. Bhushan and H. Fuchs, eds., Springer Verlag, Berlin, Heidelberg, New York, ISBN 3-540-26242-3, p. 91-119 (2006).
Link to Springer

T.E. Schäffer, “Calculation of thermal noise in an atomic force microscope with a finite optical spot size.” Nanotechnology 16, 664-670 (2005).
Abstract | PDF (299 kB)

S. Schrot, C. Weidenfeller, T.E. Schäffer, H. Robenek and H.-J. Galla, “Influence of hydrocortisone on the mechanical properties of the cerebral endothelium in vitro.” Biophysical Journal 89, 3904-3910 (2005).
Abstract | PDF (233 kB)

T.E. Schäffer and H. Fuchs, “Optimized detection of normal vibration modes of atomic force microscope cantilevers with the optical beam deflection method.” Journal of Applied Physics 97, 083524 1-8 (2005).
Abstract | PDF (395 kB) | Free PDF (s. AIP copyright note below)

V.M. Laurent, S. Kasas, A. Yersin, T.E. Schäffer, S. Catsicas, G. Dietler, A.B. Verkhovsky and J.-J. Meister, “Gradient of rigidity in the lamellipodia of migrating cells revealed by atomic force microscopy.” Biophysical Journal 89, 667–675 (2005).
Abstract | PDF (200 kB)

M. Arnoldi, T.E. Schäffer, M. Fritz and M. Radmacher, “Direct observation of single catalytic events of chitosanase by atomic force microscopy.” AZojono - Journal of Nanotechnology Online, DOI: 10.2240/azojono0107 (2005).
Abstract | PDF (224 kB)

C. Morsczeck, C. Moehl, W. Götz, A. Heredia, T.E. Schäffer, N. Eckstein, C. Sippel, K.H. Hoffmann, "In vitro differentiation of human dental follicle cells with dexamethasone and insulin." Cell Biology International 29, 567-575 (2005).
Abstract | PDF (800 kB)

Y. Jiao and T.E. Schäffer, "Accurate height and volume measurements on soft samples with the atomic force microscope." Langmuir 20, 10038-10045 (2004).
Abstract | PDF (753 kB) | Free PDF from journal

R. Proksch, T.E. Schäffer, J.P. Cleveland, R.C. Callahan and M.B. Viani, "Finite optical spot size and position corrections in thermal spring constant calibration." Nanotechnology 15, 1344-1350 (2004).
Abstract | PDF (460 kB)

T.E. Schäffer, M. Radmacher and R. Proksch, "Magnetic force gradient mapping." Journal of Applied Physics 94, 6525-6532 (2003).
Abstract | PDF (336 kB) | Free PDF (s. AIP copyright note below)

V. Ivanova, I. Makarov, T.E. Schäffer, and T. Heimburg, "Analyzing heat capacity profiles of peptide-containing membranes: Cluster formation of Gramicidin A." Biophysical Journal 84, 2427-2439 (2003).
Abstract | PDF (720 kB)

T.E. Schäffer, "Force Spectroscopy with a Large Dynamic Range Using Small Cantilevers and an Array Detector." Journal of Applied Physics 91, 4739-4746 (2002).
Abstract | PDF (97 kB) | Free PDF (s. AIP copyright note below)

A. Hoff, T. André, T.E. Schäffer, G. Jung, K.-H. Wiesmüller and R. Brock, "Lipoconjugates for the Noncovalent Generation of Microarrays in Biochemical and Cellular Assays." ChemBioChem 3, 1183-1191 (2002).
Abstract | PDF (441 kB)

Y. Jiao, D.I. Cherny, G. Heim, T.M. Jovin, and T.E. Schäffer, "Dynamic Interactions of p53 with DNA in Solution by Time-Lapse Atomic Force Microscopy." Journal of Molecular Biology 314, 233-243 (2001).
Abstract | PDF (1142 kB)

G. Hemakanthi, A. Dhathathreyan, B.U. Nair, T. Ramasami, D. Möbius and T.E. Schäffer, "Control of size of PbI2 nanocrystals using Langmuir-Blodgett films of n-octadecyl succinic acid." Colloids and Surfaces A, 181, 115-121 (2001).
Abstract | PDF (554 kB)

T.E. Schäffer, M. Richter and M.B. Viani, "Array Detector for the Atomic Force Microscope." Applied Physics Letters 76, 3644-3646 (2000).
Abstract | PDF (49 kB) | Free PDF (s. AIP copyright note below)

S. Kasas, N.H. Thomson, T.E. Schäffer, G. Dietler, S. Catsicas and P.K. Hansma, "Simulation of an atomic force microscope imaging a moving protein." Probe Microscopy 2, 37-44 (2000).
Abstract | PDF (537 kB)

A. Chand, M.B. Viani, T.E. Schäffer and P.K. Hansma, "Microfabricated Small Metal Cantilevers with Silicon Tips for Atomic Force Microscopy." Journal of Microelectromechanical Systems 9, 112-116 (2000).
Abstract | PDF (216 kB)

B.L. Smith, T.E. Schäffer, M. Viani, J.B. Thompson, N.A. Frederick, J. Kindt, A. Belcher, G.D. Stucky, D.E. Morse and P.K. Hansma, "Molecular Mechanistic Origin of the Toughness of Natural Adhesives, Fibres and Composites." Nature 399, 761-763 (1999).
Abstract | PDF (229 kB)

M.B. Viani, T.E. Schäffer, A. Chand, M. Rief, H.E. Gaub and P.K. Hansma, "Small Cantilevers for Force Spectroscopy of Single Molecules." Journal of Applied Physics 86, 2258-2262 (1999).
Abstract | PDF (151 kB)

M.B. Viani, T.E. Schäffer, G.T. Paloczi, L. Pietrasanta, B.L. Smith, J.B. Thompson, M. Richter, M. Rief, H.E. Gaub, K.W. Plaxco, A.N. Cleland, H.G. Hansma and P.K. Hansma, "Fast imaging and fast force spectroscopy of single biopolymers with a new atomic force microscope designed for small cantilevers." Review of Scientific Instruments 70, 4300-4303 (1999).
Abstract | PDF (333 kB)

T.E. Schäffer, "Neue Kraftmikroskope mit Anwendung in der Biologie." MPIbpc News 05/1999, 1-6 (1999).

T.E. Schäffer and P.K. Hansma, "Characterization and Optimization of the Detection Sensitivity of an Atomic Force Microscope for Small Cantilevers." Journal of Applied Physics 84, 4661-4666 (1998).
Abstract | PDF (188 kB) | Free PDF (s. AIP copyright note below)

T.E. Schäffer, C. Ionescu-Zanetti, R. Proksch, M. Fritz, D.A. Walters, N. Almqvist, C.M. Zaremba, A.M. Belcher, B.L. Smith, G.D. Stucky, D.E. Morse and P.K. Hansma, "Does Abalone Nacre Form by Heteroepitaxial Nucleation or by Growth through Mineral Bridges?" Chemistry of Materials 9, 1731-1740 (1997). (Was discussed in "news and views", Nature 389, 912-915 (1997).)
Abstract | PDF (471 kB)

T.E. Schäffer, M. Viani, D.A. Walters, B. Drake, E.K. Runge, J.P. Cleveland, M.A. Wendman and P.K. Hansma, "An Atomic Force Microscope for Small Cantilevers." Proceedings of the SPIE 3009, 48-52 (1997).

S. Manne, T.E. Schäffer, Q. Huo, P.K. Hansma, D.E. Morse, G.D. Stucky, and I.A. Aksay, "Gemini Surfactants at Solid-Liquid Interfaces: Control of Interfacial Aggregate Geometry." Langmuir 13, 6382-6387 (1997).
Abstract | PDF (471 kB)

S.H. Tolbert, T.E. Schäffer, J. Feng, P.K. Hansma, and G.D. Stucky, "A New Phase of Oriented Mesoporous Silicate Thin Films." Chemistry of Materials 9, 1962-1967 (1997).
Abstract | PDF (262 kB)

D.A. Walters, M. Viani, G.T. Paloczi, T.E. Schäffer, J.P. Cleveland, M.A. Wendman, G. Gurley, V. Elings, and P.K. Hansma, "Atomic Force Microscopy using Small Cantilevers." Proceedings of the SPIE 3009, 43-47 (1997).

T.E. Schäffer, J.P. Cleveland, F. Ohnesorge, D.A. Walters, and P.K. Hansma, "Studies of Vibrating Atomic Force Microscope Cantilevers in Liquid." Journal of Applied Physics 80, 3622-3627 (1996).
Abstract | PDF (1900 kB) | Free PDF (s. AIP copyright note below)

J.P. Cleveland, T.E. Schäffer and P.K. Hansma, "Probing Oscillatory Hydration Potentials using Thermal-Mechanical Noise in an Atomic Force Microscope." Physical Review B: Rapid Communications, 52, R8692-R8695 (1995).

J.P. Cleveland, T.E. Schäffer and P.K. Hansma, "Measuring Intermolecular Forces using Thermal Noise in an Atomic Force Microscope." Proc. Microscopy and Microanalysis, Jones and Begell Publishing, New York, 724-725 (1995).

R. Proksch, T.E. Schäffer, B.M. Moskowitz, E.D. Dahlberg, D.A. Bazylinski and R.B. Frankel, "Magnetic Force Microscopy of the Submicron Magnetic Assembly in a Magnetotactic Bacterium." Applied Physics Letters 66, 2582-2584 (1995).

J. Shi, J.M. Kikkawa, R. Proksch, T.E. Schäffer, D.D. Awschalom, G. Medeiros-Ribeiro, and P.M. Petroff, "Assembly of Submicrometre Ferromagnets in Gallium Arsenide Semiconductors." Nature 377, 707-710 (1995).


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